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Peyton Manning trolls brother Eli in funny Tylenol commercial

February 8, 2025 by Broncos Wire

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Peyton Manning and Eli Manning were the NFL’s most popular brothers for nearly two decades, and they have remained in the spotlight even after hanging up their cleats.

The brothers often allude to a fierce sibling rivalry in their public appearances, even if that’s perhaps not a reflection of reality. In his latest commercial for Tylenol, Peyton continued the bit.

“Everybody has something that gives them a headache,” Manning says in the ad. “For me, it’s my brother Eli. In fact, I call my headaches Eli’s. And when I feel an Eli coming on, I reach for Tylenol.

“These rapid release gels always bring fast relief. No matter how bad an Eli it is — whether its a tension Eli, a cluster Eli, or even a sinus Eli. I just pop a few of these guys and I’m right as rain.”

Click the post below to watch the commercial:

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A post shared by Peyton Manning (@peytonmanning)

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Manning, 48, won two Super Bowls during his decorated NFL career. He retired in 2016 after winning Super Bowl 50 with the Denver Broncos.

Gallery

35 photos of Peyton Manning’s son, Marshall, experiencing the NFL




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